RENAL AND ELECTROLYTE
GLOMERULONEPHRITIS
(one q only on this, Glomerulonephritis Includes nephritic and nephrotic syndrome)
PromptCauses of “Upper urinary tract” dark brown urine
(blood, protein, casts)
(blood, protein, casts)
ResponsePost strep glomerulonephritis
IgA glomerulonephritis
Membranous proliferative glomerulonephritis
Vasculitis (Egl HUS)
Tumour (Wilms etc)
Alport syndrome
INterstitial nephritis - drugs, infection, autoimmune
IgA glomerulonephritis
Membranous proliferative glomerulonephritis
Vasculitis (Egl HUS)
Tumour (Wilms etc)
Alport syndrome
INterstitial nephritis - drugs, infection, autoimmune
PromptHistorical features
ResponseFamily history
Fever
Rash - ? HSP
Diarrhoea/abdominal pain
Sore throat
Recent medications/antibiotics
Fever
Rash - ? HSP
Diarrhoea/abdominal pain
Sore throat
Recent medications/antibiotics
PromptFurther investigations
ResponseUrine microscopy and culture
ASOT ? recent streptococcal infection
Complement - Autoimmune cuase, low in post strep, normal in IgA
Skin/throat culture - Evidence of streptococcal infection
Renal biopsy - determine type of glomerulonephritis
FBC ?Plt count - reduced in HUS/TTP
ASOT ? recent streptococcal infection
Complement - Autoimmune cuase, low in post strep, normal in IgA
Skin/throat culture - Evidence of streptococcal infection
Renal biopsy - determine type of glomerulonephritis
FBC ?Plt count - reduced in HUS/TTP
PromptPeritoneal Dialysis - See ID
Response