ENDOCRINE
HYPERGLYCAEMIA
PromptCompare DKA with HHS
ResponseEpidemiology:
HSS more common than DKA
HSS more common in older (dependent) populations
Mortality higher in HHS (10%) vs DKA (1-4%)
Biochemical
HHS marked hyperglycaemia, DKA varies
HHS marked elevation in osmolality (>320) = greater water deficit.
HHS usually minimal acidosis unless from concurrent illness (Ketones may be present but trivial)
HHS AKI usually much worse.
DKA
HAGMA = Ketones
Hyperkalaemia
HHS
HAGMA = renal failure and lactate
Hyperkalaemia
HSS more common than DKA
HSS more common in older (dependent) populations
Mortality higher in HHS (10%) vs DKA (1-4%)
Biochemical
HHS marked hyperglycaemia, DKA varies
HHS marked elevation in osmolality (>320) = greater water deficit.
HHS usually minimal acidosis unless from concurrent illness (Ketones may be present but trivial)
HHS AKI usually much worse.
DKA
HAGMA = Ketones
Hyperkalaemia
HHS
HAGMA = renal failure and lactate
Hyperkalaemia