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O+G


PRETERM LABOUR

Labour after week 20 but before week 37
PromptDDX abdo pain in 3rd trimester
ResponseO+G
  • Placental abruption
  • Ovary - cyst/torsion
  • Braxton hicks contractions
  • HELLP syndrome
  • Round ligament pain
Other
  • Surgical - Appendicitis
  • GIT - Gastroenteritis
  • Genitourinary - Cystitis/UTI/Pyelo/Renal colic
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PromptRisk factors for preterm pregnancy
ResponseIdiopathic (most common)
Previous miscarriage, multiple pregnancy
Uterine abnormalities - Fibroids, bicornate uterus
Cervical abnormalities - Cervical incompetence, short cervix
Polyhydramniois
PROM
Antipartum haemorrhage
Infection (Chorioamnionitis, UTI, significant infection from any source)
Age <18 or >40
Poor antenatal care
Smoker, stimulant use
Low socioeconomic status, Ethnicity - African, asian, indigenous
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PromptHistory suggestive of premature labour
ResponseRupture of membranes - pooling amniotic fluid in vagina/history of sudden gush of fluid
Regular contractions - progressive intensity
Increasing lower back/pelvic pain
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PromptDescribe your approach in assessment of preterm labour
ResponseVital signs inc symphysis fundal height
Abdo examination - foetal lie and engagement
Sterile spec - degree of cervical dilation, PV bleeding, amniotic fluid leak/pooling
Fetal descent into pelvis
Bedside U/S - confirm FHR and lie
Hint: its the same as any assessment of labour
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PromptInvestigations in suspected premature labor
ResponseCTG trace showing contractions/foetal wellbeing
POCUS - foetal wellbeing
Ferning of amniotic fluid on microscopy - This seemed very important in ROSH MCQ’s
Vaginal pH ?6.5
Fetal fibronectin level on PV swab (Negative = 98% no delivery within 7 days)
Formal U/S ? Cervical length (>3cm usually excludes pre term labour, <1.5cm suggestive of labour)
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PromptInvestigation that can exclude preterm labor
ResponseFoetal Fibronectin on vaginal swab - If not detected labour very unlikely with next 1-2 weeks
NPV >99% (highly sensitive)
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PromptPre-arrival of preterm labor preparation

Hint: will probs be rural hospital
ResponseThink PASTED
Meds
Oxytocin 10U IM, Betamethasone 11.4 mg IM, tocolytics (Salbutamol nebs, Nifedipine 20 mg Q30 min to 3 doses), Antibiotics (Given PROM - amp/gent)
Equipment
Delivery pack + cord clamps, resuscitaire + neopuff (PPV device), U/S ?FHR, towels, suction, prayers
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PromptManagement of preterm labour
ResponseThis will almost certainly be in a rural centre - Retrieval!
Tocolytics - effective in delaying delivery 24-48 hours (in 80% of cases)
  • Nifedipine 20 mg PO Q20-30 min (Max 60 mg) if contractions persist, then QID
  • Terbutaline 0.25mg s/c
  • Salbutamol 5mg neb or IV infusion (Poorly tolerated, don’t use together with nifedipine)
  • GTN
  • ?NSAIDS - Ketorolac/Indometacin
Steroids - glucocorticoids promote foetal lung maturity if gestation <37/40
  • Betamethasone IM 11.4mg
Antibiotics - ? chorioamnionitis established (Infection most common cause - Treat!)
  • Amp/gent/metro
Neuroprotection - foetal neuroprotection
  • MgSO4 4g over 20 mins
Continuous foetal monitoring
Prepare for labour!
Transfer to obstetric centre/urgent O+G consult. Will need paeds support/NICU if preterm +++
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PromptContraindications to suppression of labour
ResponseGestation >34 wks
Fetal death in utero
Fetal malformation where pal care only is planned
Suspected fetal compromise (US or CTG) requiring urgent delivery
Placental abruption
Chorioamnionitis
Preeclampsia
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PromptContraindications to transport
ResponseActive labour >5cm cervical dilation or baby on view
Absent FHR or bradycardia
Unstable mother
Unable to transfer safely (Eg: no safe escort/skilled staff)
Cord prolapse
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