ENVIRONMENTAL
MARINE ENVENOMATION
PromptList fatal marine animal bites/stings
ResponseBox Jellyfish (Chironex) - collapse and sudden death within minutes of sting from dysrythmia and probable direct cardiotoxicity
Irukandji
Sea Snake - postsynapic neurotoxin + myotoxin. Collapse from descending flaccid paralysis
Blue ring octopus
Irukandji
Sea Snake - postsynapic neurotoxin + myotoxin. Collapse from descending flaccid paralysis
Blue ring octopus
PromptDifferentials unresponsive swimmer
ResponseTrauma - Head injury, C spine injury with cord involvement, tension PTx
Marine envenomnation - Irukandji, chironex, sea snake
Tox - Intoxication or withdrawal
Drowning
Medical problem - Asthma, SAh, Seizure
Anaphylaxis
Barotrauma with CAGE (If diving)
Marine envenomnation - Irukandji, chironex, sea snake
Tox - Intoxication or withdrawal
Drowning
Medical problem - Asthma, SAh, Seizure
Anaphylaxis
Barotrauma with CAGE (If diving)
PromptJELLYFISH
Response
PromptIrukandji general features


ResponsePain delayed 15-30 mins
Generalised pain (Not at site)
No skin changes/rash
Typically does not arrest
Generalised pain (Not at site)
No skin changes/rash
Typically does not arrest
PromptIrukandji management
ResponsePrehospital
- Vinegar, no PBI
- Fentanyl titrated to pain
- MgSO4? (controversial), PCA, Ketamine
- Control hypertension, GTN infusion SBP<160
- HDU admission
- Seek and treat complications (MI, pulmonary oedema)
PromptBOX JELLYFISH/CHIRONEX
Response
PromptBox jellyfish/Chironex general features
ResponseImmediate pain at site of sting
Characteristig laddering lesion “linear wheels”
Early cardiac arrest
Characteristig laddering lesion “linear wheels”
Early cardiac arrest
Prompt

Response

PromptWhat causes this rash
ResponseBox Jellyfish (Chironex) stings with systemic envenomnation
PromptClassic rash of chironex - Description, pathophysiology and effects of chironex venom
ResponseWidespread linear welt (“laddering” - purple/red)
Venom load from discharging nematocysts
Direct cardiotoxicity
Venom load from discharging nematocysts
Direct cardiotoxicity
PromptManagement - general
ResponseVinegar lipberally to visible sting sites and remove tentacles
Ice
Analgesia - IV opioids (+/- MgSO4)
Cardiac monitoring ? arrhythmia
antivenom
Ice
Analgesia - IV opioids (+/- MgSO4)
Cardiac monitoring ? arrhythmia
antivenom
PromptManagement - Specific
ResponseAntivenom - 1-3 amps in 100 mL/ N/S over 20 mins
PromptAntivenom indications and administration
ResponseCardiorespiratory arrest
Cardiovascular instability - Collapse, hypotension, dysrythmia
Local pain refractory to opioids
Respiratory depression - hypoventilation, difficulty swallowing/speaking/breathing
Cardiovascular instability - Collapse, hypotension, dysrythmia
Local pain refractory to opioids
Respiratory depression - hypoventilation, difficulty swallowing/speaking/breathing
PromptArrest management
ResponseAntivenom 3-6 amps IV push (IM if delay to IV access)
Vinegar to remaining tentacles + remove
Prolonged CPR if antivenom given
Airway, treat secondary injuries/causes (Eg: hypothermia, trauma), ICU referral
Vinegar to remaining tentacles + remove
Prolonged CPR if antivenom given
Airway, treat secondary injuries/causes (Eg: hypothermia, trauma), ICU referral
PromptSTINGING FISH
Response
PromptTable p42
Response
PromptBLUE RING OCTOPUS


Response
PromptBlue ring octopus venom and its effects
ResponseTetrodotoxin - sodium channel blocker neurotoxin (similar to puffer fish toxin but more rapid onset)
PromptClinical presentation
ResponseRapidly progressing descending flaccid paralysis within minutes
Early - perioral parasthesia, ptosis, blurred vision, diplopia, dysphagia
Late - progressive descending flaccid paralysis
Terminal - respiratory failure + respiratory arrest
Early - perioral parasthesia, ptosis, blurred vision, diplopia, dysphagia
Late - progressive descending flaccid paralysis
Terminal - respiratory failure + respiratory arrest
PromptManagement - blue ring octopus
ResponseIntubation and mechanical ventilation- paralysis usually resolves in 24h
No antivenom available
No antivenom available
PromptPost intubation care blue ring octopus
ResponseSedation (venom paralysis but does not affect consciousness)
Retrieval to ICU
Ongoing fluid resus
Address stem - support for parents, seek and treat other injuries etc.
Retrieval to ICU
Ongoing fluid resus
Address stem - support for parents, seek and treat other injuries etc.